Washington and Lee University Chemistry Department

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Erich S. Uffelman, Ph. D. Chemistry from California Institute of Technology Phone Number: (540) 458 - 8040 E-mail: uffelmane@wlu.edu Office Number: A427

Courses Currently Taught:

• Chem 111 General Chemistry
• Chem 250 Intermediate Inorganic Chemistry
• Chem 252 Inorganic Chemistry Laboratory
• Chem 254 Bioinorganic Chemistry
• Chem 350 Advanced Inorganic Chemistry
• Univ 202 Science in Art
• Art 380 Seminar in 17th Century Dutch Art
  

Courses Previously Taught:

• Chem 206 Survey of the Periodic Table
• Chem 207 Synthesis of Inorganic Complexes
• Chem 241 Organic Chemistry Lecture
• Chem 242 Organic Chemistry Lecture
• Chem 241L Organic Chemistry Laboratory
• Chem 242L Organic Chemistry Laboratory
• Chem 243L Organic Spectroscopy Laboratory
• Chem 295 SpecialTopics in Solid State Chemistry
• Chem 297A Materials of 17th Century Dutch Art
• Chem 297B Instrumental Methods in Art Conservation
  

Research Interests :

The Uffelman group is developing a set of novel polyamide macrocyclic ligands in order to expand the fundamental chemistry and Green Chemistry applications of iron-catalyzed oxidation reactions. Currently we are in our third iteration of ligand syntheses, which has been highly successful. This research program has, to date, involved forty-two different undergraduates, who gain experience in various NMR techniques, IR spectroscopy, inert atmosphere synthetic methods, and organic and inorganic synthesis. Sixteen of these students have done more than one summer of research in the group.

Pedagogical Research :

Novel undergraduate experiments involving NMR methodology or Green Chemistry are developed.
In addition, technical analysis of 17th century Dutch painting is used to teach an interdisciplinary non-science majors course at the interface of chemistry, physics, analytical instrumentation, history, economics, and religion. The course takes students abroad to The Netherlands for three weeks.

Research Students Supervised:

Forty-two at W&L---several for more than one summer or semester (Tamara Hopkins, T. R. Kinsey, Ryan Aday, Matthew Smith, Robert Eison, Anna Mirk, Hilary Rhodes, Jesse Taylor, Holly Layman, Charity Forstmann, Daniel Lee, Anne McElhaney, Jon Doherty, Leonard Rorrer, Carl Schulze, Stephen Hopkins, Michele Connors, Robert Hughes, Alison Cartwright, Ashley Shreves, Tom Stoklasek, Kristen Bonnema, Amy Burke, Gary Davis, Mac Everist, Tanya Watson, Ashley Acker, Bryan Carmody, Andrew Thomas, Marisa Meyer, Johnathan Coleman, Nana Ohene-Baah, Jessica Lloyd, Matthew Reilley, Jared Meyer, Emily Binns, Christopher Diebold, Carly Levin, Scot Pittman, Robert Whitener, Kehvon Clark, Elizabeth Webb)

Education:

	2006	Sabbatical leave with Professor M.G. Finn, The Scripps Research Institute
	2001	Sabbatical leave with Professor M.G. Finn, The Scripps Research Institute
	1991-1993	NIH Postdoctoral Fellow, Professor James P. Collman, Stanford University
	1991	Ph.D., NSF Predoctoral Fellow, Chemistry, California Institute of Technology, Professor Terrence J. Collins; Thesis Topic: Macrocyclic Tetraamido-N Ligands that Stabilize High-Valent Complexes of Chromium, Manganese, Iron, Cobalt, Nickel, and Copper
	1984	B.S., magna cum laude, Chemistry, Bucknell University

Awards:

• 2004 Washington and Lee Class of '65 Excellence in Teaching Award
• 1999 Certificate for Dr. Terrence Collins Presidental Green Chemistry Challenge Award
• 1999 Washington and Lee Class of '65 Excellence in Teaching Award
• 1996 Washington and Lee Class of '65 Excellence in Teaching Award
• 1991-1993 National Institutes of Health Postdoctoral Fellow, Stanford University
• 1984-1987 National Science Foundation Predoctoral Fellowship, California Institute of Technology
• 1984 ACS Susquehanna Valley Section: Outstanding Senior Chemistry Major
• 1984 Alpha Chi Sigma Senior Major with Highest Scholastic Standing
• 1984 Elizabeth M. Oliphant Prize for Highest Class Average in Chemistry or Biological Science
• 1984 Phi Beta Kappa
• 1984 Sigma Xi
• 1983 First Place Seminar in Inorganic Chemistry, ISC Convention at Temple University

Grants Awarded:

• Jeffress Research Grant Renewal---"1H-15N HMBC Spectroscopy of Complexes Relevant to Green Chemistry" Awarded July, 2007---$10,000
• Washington and Lee University---Class of '63 Lecture Series, "Recent Developments in Art Conservation and Conservation Science: Considering the Works of Rembrandt and Other Master Painters." A symposium featuring Jaap Boon (AMOLF-FOM, Amsterdam), Melanie Gifford (National Gallery of Art, Washington, DC), Petria Noble (The Mauritshuis, The Hague) October 30, 2006---$10,000
• Jeffress Research Grant Renewal---"1H-15N HMBC Spectroscopy of Complexes Relevant to Green Chemistry" Awarded July, 2005---$10,000
• Washington and Lee University---Class of '65 Excellence in Teaching, "Codifying Materials for the Presentation of Scientific Investigations into 17th Century Dutch Art" Awarded May, 2004---$6,000
• Associated Colleges of the South Mini-Keck Grant---“Codifying Materials for the Presentation of Scientific Investigations into 17th Century Dutch Art”Awarded May, 2004---$7,500
• Global Stewardship Course Development Grant---“Science in Art” Awarded March, 2004---$2,500
• National Science Foundation---Major Research Instrumentation, "Multinuclear Gradient Inverse Probe, Amplifier, and Overnight Low Temperature Dewar for High-field NMR Spectroscopy in the Chemistry Department at Washington and Lee University" Awarded August, 2003---$70,830
• Jeffress Research Grant---“¹H-¹⁵N HMBC Spectroscopy of Complexes Relevant to Green Chemistry” Awarded July, 2003---$25,000
• Hewlett-Packard Company---University Donation, "Gel Permeation Chromatography in Undergraduate Education at Washington and Lee University" Awarded August, 1999---$25,646
• Washington and Lee University ---Class of '65 Excellence in Teaching, "Development of New Cross Disciplinary Experiments for Chem 112 and Chem 252" Awarded April 1999---$5,044
• Hewlett-Packard Company---University Grants, "UV-Vis Spectroscopy in Undergraduate Education at Washington and Lee University" Awarded November, 1997---$15,788
• National Science Foundation---Instrumentation and Laboratory Improvement, "High Field Multinuclear NMR in Undergraduate Education at Washington and Lee University" Awarded May, 1996---$99,500
• Washington and Lee University ---Class of '65 Excellence in Teaching, "Development of New Cross-Disciplinary Laboratory Experiments for the New Inorganic Courses at Washington and Lee University " Awarded April, 1996---$4,375
• American Chemical Society---Petroleum Research Fund Type G, "Novel Ligands for Transition Metal and Lanthanide Complexes" Awarded April, 1995---$20,000
• Research Corporation---Cottrell College Science Award, "Novel Macrocyclic Polyamide Ligands for Lanthanide Chemistry" Awarded May, 1995---$27,000

Publications:

• Uffelman, E. S. "Teaching Science in Art: Technical Examination of 17th-Century Dutch Painting as Interdisciplinary Coursework for Science Majors and Nonmajors" J. Chem. Educ. 2007, 83, 1617-1624.
• Uffelman, E. S. "A Review of Materials for Teaching Science in Art: Technical Examination of 17th-Century Dutch Painting as Interdisciplinary Course Work for Non-Science and Science Majors" J. Chem. Educ. 2007, October Web Online, 38 pages. http://www.jce.divched.org/Journal/Supplements/index.html.
• Uffelman, E. S. "NMR Studies of Polyamide Macrocyclic Tetradentate Ligands and Their Complexes Relevant to Green Chemistry (with Other Inorganic/Organometallic Experiments)" in Modern NMR Spectroscopy in Education; Stockland, R. A.; Rovnyak, D.; Eds.; ACS Symposium Series 969; American Chemical Society: Washington, DC, 2007 300-316.
• Uffelman, E. S. "News from Online: Renewable Resources" J. Chem. Educ. 2007, 83, 220-222.
• Weng, T-C.; Hsieh, W-Y.; Uffelman, E. S.; Gordon-Wylie, S. W.; Collins, T. J.; Pecoraro, V. L.; Penner-Hahn, J. E. "XANES Evidence Against a Manganyl Species in the S3 state of the Oxygen Evolving Complex" J. Am. Chem. Soc. 2004, 126, 8070-8071.
• Uffelman, E. S. "News from Online: Green Chemistry" J. Chem. Educ. 2004, 81, 172-176.
• Uffelman, E. S.; Doherty, J. R.; Schulze, C.; Burke, A. L.; Bonnema, K.; Watson, T. T.; Lee, D. W., III "Microscale Syntheses, Reactions, and ¹H NMR Spectroscopic Investigations of Square Planar Macrocyclic Tetraamido-N Co(III) Complexes Relevant to Green Chemistry" J. Chem. Educ. 2004, 81, 325-329.
• Uffelman, E. S.; Doherty, J. R.; Schulze, C.; Burke, A. L.; Bonnema, K.; Watson, T. T.; Lee, D. W., III "Microscale Syntheses, Reactions, and ¹H NMR Spectroscopic Investigations of Square Planar Macrocyclic Tetraamido-N Cu(III) Complexes Relevant to Green Chemistry" J. Chem. Educ. 2004, 81, 182-185.
• Uffelman, E. S.; Cox, E. H.; Goehring, J. B.; Lorig, T. S.; Davis, C. M. "An NMR-Smell Module for the First Semester General Chemistry Laboratory" J. Chem. Educ., 2003, 80, 1368-1371.
• Rorrer, L. C.; Hopkins, S. D.; Connors, M. K.; Lee, D. W.,III; Smith, M. V.; Rhodes, H. J.; Uffelman, E. S. "A Convenient New Route to Tetradentate and Pentadentate Macrocyclic Ligands" Organic Letters 1999, 1, 1157-1159.
• France, M. B.; Uffelman, E. S. "Ring-Opening Metathesis Polymerization with a Well-Defined Rutheniium Carbene Complex: An Experiement for the Undergraduate Inorganic or Polymer Laboratory" J. Chem. Educ., 1999, 5, 661-665.
• Bartos, M. J.; Gordon-Wylie, S. W.; Fox, B. G.; Wright, L. J.; Weintraub, S. T.; Kauffman, K. E.; Münck, E.; Kosta, K. L.; Uffelman, E. S.; Rickard, C. E. F.; Noon, K. R.; Collins, T. J.; "Designing Ligands to Achieve Robust Oxidation Catalysts. Iron Based Systems" Coord. Chem. Rev. 1998, 174, 361-390.
• Collins, T. J.; Bartos, M. J.; Gordon-Wylie, S. W.; Fox, B. G.; Kauffmann, K. E.; Münk, E.; Rickard, C. E. F.; Weintraub, S. T.; Uffelman, E. S.; Wright, L. "Designing Ligands to Achieve Robust Atom-Transfer Oxidation Catalysts," J. Inorg. Biochem. 1995, 59, 318-319.
• Collman, J. P.; Zhang, X.; Herrmann, P. C.; Uffelman, E. S.; Boitrel, B.; Straumanis, A.; Brauman, J. I. "Congruent Multiple Michael Addition for the Synthesis of Biometric Heme Analogues," J. Am. Chem. Soc. 1994, 116, 2681-2682.
• Collman, J. P.; Zhang, X.; Lee, V. J.; Uffelman, E. S.; Brauman, J. I. "Regioselective and Enantioselective Epoxidation Catalyzed by Metalloporphyrins," Science (Washington, D. C.) 1993, 261, 1404-1411
• Collins, T. J.; Kostka, K. L.; Uffelman, E. S.; Weinberger, T. "Design, Synthesis, and Structure of a Macrocyclic Tetraamide That Stabilizes High-Valent Middle and Later Transition Metals," Inorg. Chem. 1991, 30, 4204-4210
• Collins, T. J.; Nichols, T. R.; Uffelman, E. S. "A Square-Planar Nickel(III) Complex of an Innocent Ligand System," J. Am. Chem. Soc. 1991, 113, 4708-4709.
• Collins, T. J.; Powell, R. D.; Slebodnick, C.; Uffelman, E. S. "Stable Highly Oxidizing Cobalt complexes of Macrocyclic Tetraamide Ligands," J. Am. Chem. Soc. 1991, 113, 8419-8425.
• Collins, T. J.; Kostka, K. L.; Münk, E.; Uffelman, E. S. "Stabilization of Mononuclear Five-Coordinate Iron (IV)," J. Am. Chem. Soc. 1990, 112, 5637-5639.
• Collins, T. J.; Powell, R. D.; Slebodnick, C.; Uffelman, E. S. "A Water-Stable Manganese(V)-Oxo Complex: Definitive Assignment of a v(Mn-O) Triple Bond Infrared Vibration," J. Am. Chem. Soc. 1990, 112, 899-901.
• Collins, T. J.; Slebodnick, C.; Uffelman, E. S. "Chromium(V)-Oxo Complexes of Macrocyclic Tetraamido-N Ligands Tailored for Highly Oxidized Middle Transition Metal Complexes: A ¹⁸O-Labelling Reagent and a Structure with Four Nonplanar Amides," Inorg. Chem. 1990, 29, 3432-3436.
• Collins, T. J.; Uffelman, E. S. "The First Macrocyclic Square-Planar Cobalt(III) Complex Relieves Ring Strain by Forming a Nonplanar Amide," Angew. Chem. Int. Ed. Engl. 1989, 28, 1509-1511.

Patents:

• Collins, T. J.; Gordon-Wylie, S. W.; Woomer, C. G.; Horwitz, C. P.; Uffelman, E. S. "Oxidation Catalysis" PCT Int. Appl. (1998), 62 pp. CODEN: PIXXD2 WO 9858735 A1 19981230 CAN 130:111826 AN 1999:27764
• Collman, J. P.; Zhang, X.; Uffelman, E. S. U.S. Patent 5 274 090: 1993

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